diff --git a/gateway/run_startup.py b/gateway/run_startup.py
index cd06d6d498..bad85a1ebf 100644
--- a/gateway/run_startup.py
+++ b/gateway/run_startup.py
@@ -893,7 +893,26 @@ class GatewayStartupMixin:
                 send_relay_policy()
         except Exception:
             logger.warning("relay adapter registration failed at gateway startup", exc_info=True)
-        GatewayStartupMixin._register_config_hooks("shell-hook registration failed at gateway startup")
+        GatewayStartupMixin._register_launch_profile_config_hooks()
+
+    @staticmethod
+    def _register_launch_profile_config_hooks() -> None:
+        """The launch profile's ``hooks:`` block, registered under ITS runtime scope when multiplexing.
+
+        Startup runs before any turn scope exists and ``get_secret`` fails closed outside a scope
+        while multiplexing is on, so the launch profile needs the scope secondaries already get
+        (``_start_secondary_profile_adapters``) or its ``secret_env`` targets cannot resolve.
+        """
+        from agent.secret_scope import is_multiplex_active
+        if not is_multiplex_active():
+            GatewayStartupMixin._register_config_hooks(
+                "shell-hook/webhook registration failed at gateway startup", level=logging.WARNING)
+            return
+        from gateway.run import _profile_runtime_scope
+        from hermes_constants import get_process_hermes_home
+        with _profile_runtime_scope(get_process_hermes_home()):
+            GatewayStartupMixin._register_config_hooks(
+                "shell-hook/webhook registration failed at gateway startup", level=logging.WARNING)
 
     @staticmethod
     def _register_config_hooks(fail_fmt: str, *fail_args, level: int = logging.DEBUG) -> None:
diff --git a/tests/gateway/test_startup_launch_profile_hooks_scope.py b/tests/gateway/test_startup_launch_profile_hooks_scope.py
new file mode 100644
index 0000000000..ffc5a647f1
--- /dev/null
+++ b/tests/gateway/test_startup_launch_profile_hooks_scope.py
@@ -0,0 +1,68 @@
+"""Multiplex invariant: the launch profile's ``hooks:`` block registers at gateway startup.
+
+Startup runs before any turn scope exists. With ``multiplex_profiles`` on, ``get_secret`` fails
+closed outside a scope, so the unscoped launch-profile registration raised on the first
+``hooks.outbound[].secret_env`` target and ``_register_config_hooks`` swallowed it at DEBUG level —
+every launch-profile outbound webhook was silently dropped. Regression for the #108319 follow-up.
+"""
+from __future__ import annotations
+
+import logging
+
+from agent import secret_scope
+from gateway.run_startup import GatewayStartupMixin
+
+
+def _capture_registration(monkeypatch, hooks_cfg):
+    seen: dict = {}
+    import agent.outbound_webhooks as ow
+    import agent.shell_hooks as sh
+    import hermes_cli.config as cfgmod
+
+    def fake_register_outbound(cfg):
+        seen["targets"] = ow.iter_configured_targets(cfg)
+        seen["scope"] = secret_scope.current_secret_scope()
+
+    monkeypatch.setattr(cfgmod, "load_config", lambda: hooks_cfg)
+    monkeypatch.setattr(sh, "register_from_config", lambda cfg, accept_hooks=False: None)
+    monkeypatch.setattr(ow, "register_from_config", fake_register_outbound)
+    return seen
+
+
+def test_launch_profile_webhooks_register_signed_under_multiplex(tmp_path, monkeypatch, caplog):
+    launch_home = tmp_path / ".hermes"
+    launch_home.mkdir()
+    (launch_home / ".env").write_text("MY_HOOK_SECRET=s3cret-of-launch\n")
+    monkeypatch.setenv("HERMES_HOME", str(launch_home))
+    monkeypatch.delenv("MY_HOOK_SECRET", raising=False)
+    cfg = {"hooks": {"outbound": [
+        {"url": "https://hooks.example/signed", "events": ["on_session_end"], "secret_env": "MY_HOOK_SECRET"},
+        {"url": "https://hooks.example/plain", "events": ["on_session_end"]},
+    ]}}
+    seen = _capture_registration(monkeypatch, cfg)
+
+    secret_scope.set_multiplex_active(True)
+    try:
+        assert secret_scope.current_secret_scope() is None  # startup: no turn scope yet
+        with caplog.at_level(logging.WARNING, logger="gateway.run_startup"):
+            GatewayStartupMixin._register_launch_profile_config_hooks()
+    finally:
+        secret_scope.set_multiplex_active(False)
+
+    assert seen.get("scope") is not None, "registration must run inside the launch profile's scope"
+    assert [t.url for t in seen["targets"]] == ["https://hooks.example/signed", "https://hooks.example/plain"]
+    assert seen["targets"][0].secret == "s3cret-of-launch"
+    assert "registration failed" not in caplog.text
+
+
+def test_registration_failure_is_a_warning_not_debug(monkeypatch, caplog):
+    """A dropped hook block must be visible: the swallow used to log at DEBUG."""
+    import hermes_cli.config as cfgmod
+
+    def boom():
+        raise RuntimeError("config exploded")
+
+    monkeypatch.setattr(cfgmod, "load_config", boom)
+    with caplog.at_level(logging.WARNING, logger="gateway.run_startup"):
+        GatewayStartupMixin._register_launch_profile_config_hooks()
+    assert any(r.levelno == logging.WARNING and "registration failed" in r.getMessage() for r in caplog.records)